Who We are

We provide innovative solutions so that
mankind can lead a healthy life for a long time.

Who We are

History

Jump Up

2020~
  • 2023
    • US Patent Registration (No. 11,566,220)
      “Cell Line consecutively expressing HLA-G protein and method for preparing the same”
    • JP Patent Registration (No. 7261510)
      ”Production Methods of Immune-tolerant Extracellular Vesicle containing Lactate Dehydrogenase B
      and Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and Therapeutic Composition
      for Anti-Cancer thereof”
    • US Patent Registration (No. 17,611,046)
      ”Production Methods of Immune-tolerant Extracellular Vesicle containing Lactate Dehydrogenase B and Peroxisome proliferator-activated receptor gamma coactivator 1-alpha and Therapeutic Composition for Anti-Cancer thereof”
  • 2022
    • Received Government R&D Support for 2022 SME Technology Innovation Development Project
      “Development of a functional cosmetic prototype that helps alleviate hair loss symptoms using extracellular vesicles that have the effect of improving blood circulation and normalizing the hair cycle”
    • Received Certificate of national New Excellent Technology (NET) extension for
      "Manufacturing Technology for Cryopreservation of Cells and Tissues Including Immune-Tolerized
      Human Mesenchymal Stem Cell-derived Extracellular Vesicles“
    • Published Research Article in the International Journal of Biological Sciences (IJBS)
      "The Different Immune Responses by Age Are due to the Ability of the Fetal Immune System to Secrete
      Primal Immunoglobulins Responding to Unexperienced Antigens" (2022 IF: 10.85)
    • Received ISO 9001 & 14001 Certificates for "Manufacture of Stem Cell Culture Media Cosmetics”
      and “Production of Immune-Tolerized Stem Cell-Derived Extracellular Vesicle (MBTC-MSC-EXO)
    • Received Certificate of Venture Enterprise (No. 20220907020044)
    • Signed Business Agreement with Chungbuk Free Economic Zone Authority (CBFEZ) for
      “Stem Cell-Derived Extracellular Vesicle Therapeutics Research and Development Project”
  • 2021
    • JP Patent Registration (No. 6977051)
      “Cell Line consecutively expressing HLA-G protein and method for preparing the same”
    • US Patent Registration (No. 11,077,145)
      “A Method for mass production of proteins from mesenchymal stem cells”
    • KR Patent Registration (No. 10-2252325)
      "Production Methods of Immune-tolerant Extracellular Vesicles containing fetal-derived
      primal immunoglobulins“
    • Received Certificate of national New Excellent Technology (NET) for
      "Manufacturing Technology of Immune-tolerized Extracellular Vesicles for Atopy Improvement"
  • 2020
    • Published Research Article in Journal of Extracellular Vesicles
      "Study of immune-tolerized cell lines and extracellular vesicles inductive environment promoting
      continuous expression and secretion of HLA-G from semi-allograft immune tolerance during pregnancy“
      (2022 IF:25.841)
    • Received Government R&D Support for 2020 Start-up Growth Technology Development Project
      “Development of animal-derived ingredients and DMSO-free compositions for cryopreservation of cells
      and tissues containing immune-tolerized extracellular vesicles”
    • Received Certificate of national New Excellent Technology (NET) for
      "Manufacturing Technology for Cryopreservation of Cells and Tissues Including Immune-Tolerized
      Human Mesenchymal Stem Cell-derived Extracellular Vesicles“
    • 2 KR Trademark Registrations of "RETROPHA-G“ for Cosmetics and Pharmaceuticals
    • Received ISO 9001 & 14001 Certificates for "Manufacture of Stem Cell Culture Media Cosmetics”
      and “Production of Immune-Tolerized Stem Cell-Derived Extracellular Vesicle (MBTC-MSC-EXO)

Growth

2008~
2019
  • 2019
    • Establishment of the Institutional Review Board (IRB)
    • JP Patent Registration (No. P6609034)
      "A Method for mass production of proteins from mesenchymal stem cells"
    • KR Patent Registration (NO.10-2049505) "Production Methods of Immune-tolerant Extracellular Vesicle containing Lactate Dehydrogenase B and Peroxisome proliferator-activated receptor gamma coactivator
      1-alpha and Therapeutic Composition for Anti-Cancer thereof"
    • Registered New Cosmetic Ingredient in Personal Care Products Council (PCPC)
      “INCI : Human Amniotic Fluid Mesenchymal Stem Cell/Trophoblast Cell Exosomes
      (TRADE NAME : MBTC-MSC-EXO)“
    • Received Award from the Ministry of Science and ICT commemorating the 40th anniversary of the founding
      of the Korea Industrial Technology Association
    • Received ISO 9001 & 14001 Certificates for "Manufacture of Stem Cell Culture Liquid Cosmetics”
    • KR Patent Registration (No. 10-2018609)
      "A composition for cells or tissues cryopreservation comprising culture media from
      mesenchymal stem cells"
    • Received Government R&D Support for 2019 Start-up Growth Technology Development Project
      “Development of functional cosmetics that help alleviate dryness caused by atopic skin using
      immune-tolerized natural exosomes”
    • KR Patent Registration (No.10-1980726)
      "Cell Line Consecutively Expressing HLA-G Protein and Method for Preparing the same"
  • 2018
    • Received Promising Export Small and Medium Enterprise
    • Received Certificate of Venture Enterprise (No. 20180109452)
    • Received Government R&D Support for 2018 Start-up Growth Technology Development Project
      “Development of prototype exosome cosmetics for atopic dermatitis with skin barrier strengthening
      and immune response modulating effects”
  • 2016
    • Established Corporate Affiliation Research Institute (Stemmedicare R&D Center)
    • Received ISO 9001 & 14001 Certificates for “Development and Sale of Stem cell culture liquid cosmetics”
    • Received Certificate of Venture Business (No. 20160109070)
  • 2015
    • KR Patent Registration (No.10-1566450)
      "A Method for mass production of proteins from mesenchymal stem cells"
    • KR Patent Registration (No.10-1252829)
      "Array apparatus for separation of single cell"
    • KR Patent Registration (No.10-1179553)
      “Compartment unit for cell culture and array having the same"
  • 2013
    • Established Stemmedicare Co., Ltd.
  • 2008
    • Established StemMedience Co., Ltd